Logical design of oral glucose ingestion pattern minimizing blood glucose in humans
نویسندگان
چکیده
منابع مشابه
Pathways for glucose disposal after meal ingestion in humans.
To characterize postprandial glucose disposal more completely, we used the tritiated water technique, a triple-isotope approach (intravenous [3-H(3)]glucose and [(14)C]bicarbonate and oral [6,6-(2)H(2)]glucose) and indirect calorimetry to assess splanchnic and peripheral glucose disposal, direct and indirect glucose storage, oxidative and nonoxidative glycolysis, and the glucose entering plasma...
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The plasma glucose excursion may influence the metabolic responses after oral glucose ingestion. Although previous studies addressed the effects of hyperglycemia in conditions of hyperinsulinemia, it has not been evaluated whether the route of glucose administration (oral vs. intravenous) plays a role. Our aim was to determine the effects of moderately controlled hyperglycemia on glucose metabo...
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This study aims to reveal the importance of chemical senses in glucose kinetics and autonomic nervous activity by imposing interventions during glucose intake. The glucose-loading test was applied to seven healthy individuals. Three successive oral glucose-loadings induced a gradual downward shift in the blood glucose curves (BGC) together with increased salivary α-amylase activity (s-AMY) and ...
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Background: Diabetes mellitus (DM) is a common chronic disease with diverse complications. About 10% of the earth's population suffer from this disease. For smart control of the blood glucose in DM patients, an artificial pancreas was designed and simulated by a predictive sliding mode controller considering the time delay of insulin effect. Method: In this method, one of the time-delay glucos...
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BACKGROUND AND AIMS When a high fat oral load is followed several hours later by further ingestion of nutrients, there is an early postprandial peak in plasma triacylglycerol (TG). The aim of this study was to investigate the location and release of lipid from within the gastrointestinal tract. METHODS Ten healthy patients undergoing oesopho-gastro-duodenoscopy (OGD) were recruited. At t=0, a...
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ژورنال
عنوان ژورنال: npj Systems Biology and Applications
سال: 2019
ISSN: 2056-7189
DOI: 10.1038/s41540-019-0108-1